Fish Oil May Help Improve Protein Balance in People with COPD
This clinical trial looked at whether omega-3 fatty acids (EPA and DHA) could help improve how the body handles protein in people with moderate to severe chronic obstructive pulmonary disease (COPD). COPD is often linked to muscle loss and disrupted protein metabolism, so researchers wanted to see if omega-3s could help.
Thirty-two adults with COPD were randomly assigned to take a high dose (3.5 grams) of EPA+DHA, a low dose (2.0 grams), or a placebo (olive oil) daily for four weeks. Using advanced tracer techniques, the researchers measured how much protein was being broken down and rebuilt in the body, both between meals and after eating a protein-containing meal. They also assessed muscle mass and physical function.
After four weeks, blood levels of EPA and DHA rose as expected in both omega-3 groups. The study was designed to determine whether omega-3 supplementation could reduce unwanted protein breakdown during fasting periods and improve the body’s ability to build protein after eating, in a dose-related manner.
What this means for you
For people managing COPD, this research suggests that omega-3 supplementation may play a supportive role in protein metabolism, which is relevant to preserving muscle health. As with all supplement research, this is not a treatment for COPD, and individuals should talk to their healthcare provider before making changes to their supplement routine.
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The American journal of clinical nutrition · 2022-09-02 · DOI: 10.1093/ajcn/nqac138
Read the original source ↗This summary is for educational purposes only and is not medical advice. Always talk to your healthcare provider before making changes to your supplement routine.