How Micronutrients and Omega-3s May Support Healthy Aging

This review paper looks at how aging affects the body at a cellular level, particularly focusing on mitochondria—the energy-producing structures inside cells. Starting around age 40-50, many organs begin a gradual decline in function, and the researchers link this partly to shortfalls in key micronutrients.

The authors highlight several nutrients—vitamins B, C, D, and E, along with iron, selenium, and zinc—as important cofactors for mitochondrial function, antioxidant defenses, immune health, and the body’s ability to resolve inflammation. They note that low intake of these nutrients, combined with age-related physical changes and common medications, can make deficiencies more likely in older adults.

The paper also discusses omega-3 fatty acids EPA and DHA, noting that low levels of these are common in older populations and are associated with increased inflammation and functional decline. The authors suggest EPA and DHA may work together with micronutrients to help manage inflammation, though they emphasize that nutrients interact as a network rather than acting alone, and effects may vary between individuals.