A growing library of the omega-3 research we're following — summarized and categorized so you can find what matters to you.
This review explains why DHA's promising mechanisms in Alzheimer's disease haven't consistently translated into clear clinical trial benefits.
This review explains how DHA (omega-3) and arachidonic acid (omega-6) are structurally embedded in brain cell membranes and released to support neuron signaling, growth, and inflammation control, with relevance to research on depression, Alzheimer's, and Parkinson's disease.
In mice, a lysophosphatidylcholine-bound omega-3 supplement raised brain EPA but not DHA levels, with effects varying by Alzheimer's-linked APOE gene type and treatment duration.
Marine-derived lysophosphatidylcholine appears to transport omega-3 DHA into the brain more efficiently than other fat forms, via a specific brain-barrier transporter protein.
In a mouse model of Alzheimer's disease, higher brain omega-3 levels were linked to less cognitive decline and increased levels of a nerve-protecting protein called MAG.
A research review links dietary DHA/EPA to multiple brain-aging pathways, with the clearest benefits seen in people who start with low omega-3 status.