RCT Jul 1, 2019 How Blocking an Omega-3 Processing Enzyme Affects Muscle Breakdown in Mice In mice, blocking the enzyme that activates omega-3 fats increased markers of muscle protein breakdown, suggesting omega-3s may help preserve muscle mainly by limiting degradation rather than boosting synthesis. Autophagy Gene Expression Metabolism Muscle Loss Read the summary →
Observational May 28, 2019 How Omega-3 DHA and Vitamin E Tocotrienol Affect Fat Droplets in Breast Cancer Cells Combining omega-3 DHA with delta-tocotrienol reduced lipid droplet buildup and increased lipid breakdown (lipophagy) in triple-negative breast cancer cells grown in the lab. Autophagy Cancer Gene Expression Lipophagy Metabolism Read the summary →
Review/News Jul 1, 2021 How EPA Helps Kidney Cells Clear Out Excess Fat In mice and cultured kidney cells, EPA supplementation helped restore impaired cellular 'clean-up' (autophagy) processes disrupted by excess dietary fat. Autophagy Fatty Liver Gene Expression Lipophagy Metabolism Obesity Phospholipids Read the summary →
RCT Mar 3, 2025 Omega-3s May Support Brain Function During Heat Stress by Boosting Cellular Cleanup In heat-stressed mice, omega-3 fatty acids improved cognitive function and protected brain cells, apparently by restoring a cellular cleanup process (autophagy) through changes to the PI3K-Akt-mTOR signaling pathway. Autophagy Brain Cognition Gene Expression Read the summary →