A growing library of the omega-3 research we're following — summarized and categorized so you can find what matters to you.
In a mouse neuroblastoma model, high-dose omega-6 (ARA) accelerated tumor growth while high-dose omega-3 (DHA) caused tumor shrinkage or regression via competing lipid signaling pathways.
MFSD2A is a sodium-dependent transporter that carries DHA-bound lysophosphatidylcholine across cell barriers, playing a well-established role in brain DHA supply and blood-brain barrier formation, with more tentative roles in other tissues and diseases.
A review of gastrointestinal cancer surgery patients finds immunonutrition (including omega-3s) most consistently reduces postoperative infections in nutritionally at-risk patients, though effects on recovery and survival remain unclear.
Researchers are developing new delivery systems, like liposomes and nanoparticles, to help omega-3-derived resolving compounds (SPMs) work better and last longer in the body.
This review found that fatty acid effects on colorectal cancer risk are complex and vary by fatty acid type, food source, body tissue, sex, and cancer site rather than following simple 'good fat/bad fat' categories.
In lab-grown prostate cancer cells, DHA increased the cell-killing effects of a PARP inhibitor and, in one cell line, enzalutamide, through different cell-death pathways.