A growing library of the omega-3 research we're following — summarized and categorized so you can find what matters to you.
In a mouse neuroblastoma model, high-dose omega-6 (ARA) accelerated tumor growth while high-dose omega-3 (DHA) caused tumor shrinkage or regression via competing lipid signaling pathways.
In obese rats, krill oil supplementation lowered blood cholesterol and reversed diet-induced changes in sortilin and TNF-α levels in the liver and fat tissue.
At the same dose, krill oil raised blood EPA and DHA levels about 1.5 times more than fish oil over 12 weeks.
MFSD2A is a sodium-dependent transporter that carries DHA-bound lysophosphatidylcholine across cell barriers, playing a well-established role in brain DHA supply and blood-brain barrier formation, with more tentative roles in other tissues and diseases.
In obese mice, krill oil's omega-3 phospholipids increased intestinal fat-burning and reduced body weight and liver fat more effectively than omega-3 triglycerides.
This review explains why DHA's promising mechanisms in Alzheimer's disease haven't consistently translated into clear clinical trial benefits.