Evidence, in plain English

ALP Lipid Lab Library

A growing library of the omega-3 research we're following — summarized and categorized so you can find what matters to you.

Type

Population

Observational Jul 23, 2025

Krill Oil Combined With Curcumin and Silymarin Studied in Mice With Fatty Liver

In mice, a krill oil, curcumin, and silymarin combination reduced high-fat-diet liver fat buildup and shifted genes tied to fat metabolism and inflammation.

Fatty Liver Gene Expression Krill Oil Liver Health Metabolism Phospholipids

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Observational Apr 1, 2026

Low Blood Levels of EPA Linked to Heart Failure with Preserved Pumping Function in Mouse and Human Studies

In mice and human blood samples, low EPA levels were linked to worse heart-filling problems, and high-dose EPA improved heart function in mice through a TREM2-dependent cell-clearing pathway.

Gene Expression Heart Health Immune System

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RCT Feb 1, 2020

Krill Oil May Help Protect the Liver and Spleen from Iron Overload Damage in Rats

In rats with iron overload, krill oil reduced liver and spleen damage markers and improved oxidative stress balance in tissue.

Fatty Liver Gene Expression Krill Oil Liver Health Phospholipids

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RCT Mar 9, 2022

Omega-3 Phospholipids May Support Gut Barrier Function During Inflammatory Stress in Mice

In mice, DHA- and EPA-enriched phospholipids protected the intestinal barrier from toxin-induced damage through a sirtuin 1-dependent pathway.

Autophagy Gene Expression Immune System Phospholipids

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Observational Mar 1, 2020

Fish Oil Boosts Liver’s Cellular Cleanup Process in Alcohol-Exposed Rats

In rats, replacing part of dietary olive oil with fish oil reduced ethanol-related liver stress and appeared to restore normal liver cell cleanup (autophagy) activity.

Autophagy Fatty Liver Gene Expression Liver Health

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RCT Jul 1, 2019

How Blocking an Omega-3 Processing Enzyme Affects Muscle Breakdown in Mice

In mice, blocking the enzyme that activates omega-3 fats increased markers of muscle protein breakdown, suggesting omega-3s may help preserve muscle mainly by limiting degradation rather than boosting synthesis.

Autophagy Gene Expression Metabolism Muscle Loss

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ALP Lipid Lab Library

Krill Oil Combined With Curcumin and Silymarin Studied in Mice With Fatty Liver

Low Blood Levels of EPA Linked to Heart Failure with Preserved Pumping Function in Mouse and Human Studies

Krill Oil May Help Protect the Liver and Spleen from Iron Overload Damage in Rats

Omega-3 Phospholipids May Support Gut Barrier Function During Inflammatory Stress in Mice

Fish Oil Boosts Liver’s Cellular Cleanup Process in Alcohol-Exposed Rats

How Blocking an Omega-3 Processing Enzyme Affects Muscle Breakdown in Mice

The ALP Lipid Lab

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