Krill Oil and a Key Fat-Regulating Protein in Obese Rats
In obese rats, krill oil supplementation lowered blood cholesterol and reversed diet-induced changes in sortilin and TNF-α levels in the liver and fat tissue.
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In obese rats, krill oil supplementation lowered blood cholesterol and reversed diet-induced changes in sortilin and TNF-α levels in the liver and fat tissue.
In mice, a sucrose-free sunflower oil-based high-fat diet caused gut dysbiosis and steatohepatitis-like liver changes, while a fish oil-based diet did not show these effects.
Removing a liver enzyme (ELOVL2) altered how male and female mice process omega-3 fats, especially DHA in the heart, revealing the liver's role in sex-based omega-3 differences.
A malaria-related compound also abbreviated 'DHA' (not omega-3 DHA) was shown in lab and rodent studies to trigger copper- and iron-related cell death pathways in liver stellate cells, a mechanism relevant to liver fibrosis research.
In a meta-analysis of preterm infants, IV fat emulsions containing fish oil showed a consistent trend toward lower liver disease risk compared to soybean oil alone, but evidence certainty was low.
In a mouse model of severe alcohol-related liver disease, resolvin D1 reduced liver injury, inflammation, and fibrosis-related gene activity while improving liver regeneration.