Evidence, in plain English

ALP Lipid Lab Library

A growing library of the omega-3 research we're following — summarized and categorized so you can find what matters to you.

Type

Population

Review/News Sep 29, 2026

How the Body Moves DHA Into the Brain: The Role of MFSD2A

MFSD2A is a sodium-dependent transporter that carries DHA-bound lysophosphatidylcholine across cell barriers, playing a well-established role in brain DHA supply and blood-brain barrier formation, with more tentative roles in other tissues and diseases.

Brain Cognition Cancer Eye Health Gene Expression Lysophosphatidylcholine (LPC) Membranes Phospholipids Prenatal Pediatric

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RCT Jun 1, 2025

Omega-3 Rich Maternal Diet Boosts Brain-Building Fats in Developing Mouse Fetuses

A high omega-3 maternal diet increased DHA-rich brain phospholipids and improved neuronal membrane structure in mouse fetuses during gestation.

Brain Cognition Lysophosphatidylcholine (LPC) Membranes Phosphatidylcholine (PC) Phosphatidylethanolamine (PE) Phospholipids Prenatal Pediatric

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RCT Jul 12, 2024

Omega-3 Phospholipid Supplement Reduces Brain Damage in Newborn Mice After Oxygen Deprivation

In newborn mice, an omega-3 phospholipid supplement reduced brain tissue damage after oxygen-deprivation injury but did not improve behavioral outcomes or boost stem cell therapy.

Brain Cognition Lysophosphatidylcholine (LPC) Myelin Phospholipids Prenatal Pediatric Stem Cells

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Review/News May 8, 2023

Scientists Map How a Brain Transporter Flips Omega-3 Fats Into the Brain

Researchers used cryo-EM imaging to reveal the step-by-step molecular mechanism by which the Mfsd2a transporter carries DHA and ALA across the blood-brain barrier.

Brain Cognition Lysophosphatidylcholine (LPC) Membranes Phospholipids

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RCT Apr 1, 2025

A Special Omega-3 Form Raises Brain EPA, But Not DHA, and Effects Differ by Alzheimer’s Gene Type

In mice, a lysophosphatidylcholine-bound omega-3 supplement raised brain EPA but not DHA levels, with effects varying by Alzheimer's-linked APOE gene type and treatment duration.

Alzheimer's Brain Cognition Gene Expression Lysophosphatidylcholine (LPC) Membranes Phospholipids

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Review/News Mar 30, 2023

How Fish-Derived Lysophosphatidylcholine Delivers Omega-3s to the Brain

Marine-derived lysophosphatidylcholine appears to transport omega-3 DHA into the brain more efficiently than other fat forms, via a specific brain-barrier transporter protein.

Alzheimer's Brain Cognition Lysophosphatidylcholine (LPC) Membranes Mood Mental Health Phospholipids

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ALP Lipid Lab Library

How the Body Moves DHA Into the Brain: The Role of MFSD2A

Omega-3 Rich Maternal Diet Boosts Brain-Building Fats in Developing Mouse Fetuses

Omega-3 Phospholipid Supplement Reduces Brain Damage in Newborn Mice After Oxygen Deprivation

Scientists Map How a Brain Transporter Flips Omega-3 Fats Into the Brain

A Special Omega-3 Form Raises Brain EPA, But Not DHA, and Effects Differ by Alzheimer’s Gene Type

How Fish-Derived Lysophosphatidylcholine Delivers Omega-3s to the Brain

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