Diet and Natural Supplements for Fatty Liver Disease: A Research Review
A research review summarizes how various diets and nutraceuticals, including omega-3s, have been studied for their potential role in supporting liver health in NAFLD.
A growing library of the omega-3 research we're following — summarized and categorized so you can find what matters to you.
A research review summarizes how various diets and nutraceuticals, including omega-3s, have been studied for their potential role in supporting liver health in NAFLD.
In people with a history of severe hypertriglyceridemia and pancreatitis on a low-fat diet, a carboxylic acid omega-3 formulation showed somewhat higher short-term absorption than an ethyl ester formulation, but both raised long-term blood omega-3 levels similarly.
In human liver and intestinal cell models, EPA and DHA altered gene activity in ways that reduced bile acid buildup and toxicity.
In cell and mouse studies, combining omega-3 fatty acids with the drug rapamycin increased cancer cell death and reduced the drug's metabolic side effects.
In a Japanese population, fish-related blood and urine metabolites were linked to lower triglycerides, lower blood pressure, and higher HDL cholesterol, with the strongest effects seen for raw and high-omega-3 fish.
In mice, a krill oil, curcumin, and silymarin combination reduced high-fat-diet liver fat buildup and shifted genes tied to fat metabolism and inflammation.