A growing library of the omega-3 research we're following — summarized and categorized so you can find what matters to you.
In lab-grown neurons from a patient with a rare genetic synapse disorder, DHA increased a key synaptic protein and improved several measures of neuronal network activity.
This review explains how DHA (omega-3) and arachidonic acid (omega-6) are structurally embedded in brain cell membranes and released to support neuron signaling, growth, and inflammation control, with relevance to research on depression, Alzheimer's, and Parkinson's disease.
Pooled data from 16 RCTs showed omega-3 supplementation had a small, borderline-significant benefit on ADHD outcomes, with stronger effects on cognitive tests than behavior ratings.
Marine-derived lysophosphatidylcholine appears to transport omega-3 DHA into the brain more efficiently than other fat forms, via a specific brain-barrier transporter protein.
In rats, an omega-3-enriched diet after weaning reversed depression-like behavior and myelin abnormalities in offspring caused by a mother's high-fat diet during pregnancy.
In mice, lifelong omega-3 deficiency disrupted brain myelin development and was linked to memory and emotional changes in adulthood.