How Cells Transport Omega-3 Fats to Build Myelin in the Brain
In mice, loss of the omega-3 lysolipid transporter Mfsd2a in brain precursor cells disrupted normal maturation of myelin-producing cells and reduced brain myelination.
A growing library of the omega-3 research we're following — summarized and categorized so you can find what matters to you.
In mice, loss of the omega-3 lysolipid transporter Mfsd2a in brain precursor cells disrupted normal maturation of myelin-producing cells and reduced brain myelination.
In newborn mice, an omega-3 phospholipid supplement reduced brain tissue damage after oxygen-deprivation injury but did not improve behavioral outcomes or boost stem cell therapy.
A specialized brain transporter protein, MFSD2A, moves omega-3 DHA across the blood-brain barrier by binding it in a lysophosphatidylcholine form.
In rats, an omega-3-enriched diet after weaning reversed depression-like behavior and myelin abnormalities in offspring caused by a mother's high-fat diet during pregnancy.
A systematic review found limited but consistent evidence that omega-3 supplementation during pregnancy may modestly improve some measures of children's cognitive development.
In a mouse model of Alzheimer's disease, higher brain omega-3 levels were linked to less cognitive decline and increased levels of a nerve-protecting protein called MAG.