DHA Reshapes Brain Cell Membranes and Mitochondria in ApoE4 Mouse Model
In ApoE4 mice, dietary DHA rebalanced rigid, inflamed brain cell membranes and restored mitochondrial energy function, linking liver fat problems to brain membrane changes.
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In ApoE4 mice, dietary DHA rebalanced rigid, inflamed brain cell membranes and restored mitochondrial energy function, linking liver fat problems to brain membrane changes.
DHA appears to regulate brain inflammation through multiple connected pathways, including cell membrane structure, mitochondrial function, and inflammation-resolving molecules.
A new chromatography method purified Antarctic krill oil phospholipids to over 95% purity with 81% recovery.
An engineered bacterial enzyme achieved an 88.6% conversion rate when producing DHA-enriched phosphatidylethanolamine, the highest yield reported to date for this process.
Omega-3-containing phosphatidylserine molecules accumulate at brain synapses during development, depending on diet, lysosomal fat recycling, and neuronal activity.
In mice, low DHA caused retinal cells to swap in oxidation-prone omega-6 fats, driving oxidative stress and immune activation linked to vision decline, which diet-based DHA restoration reversed.