A growing library of the omega-3 research we're following — summarized and categorized so you can find what matters to you.
This review summarizes research suggesting omega-3 fatty acids may support recovery from exercise-induced muscle damage through anti-inflammatory and antioxidant activity.
Removing a liver enzyme (ELOVL2) altered how male and female mice process omega-3 fats, especially DHA in the heart, revealing the liver's role in sex-based omega-3 differences.
Pooled data from 16 RCTs showed omega-3 supplementation had a small, borderline-significant benefit on ADHD outcomes, with stronger effects on cognitive tests than behavior ratings.
In mice, loss of the omega-3 lysolipid transporter Mfsd2a in brain precursor cells disrupted normal maturation of myelin-producing cells and reduced brain myelination.
In newborn mice, an omega-3 phospholipid supplement reduced brain tissue damage after oxygen-deprivation injury but did not improve behavioral outcomes or boost stem cell therapy.
Researchers used cryo-EM imaging to reveal the step-by-step molecular mechanism by which the Mfsd2a transporter carries DHA and ALA across the blood-brain barrier.
In mice, a lysophosphatidylcholine-bound omega-3 supplement raised brain EPA but not DHA levels, with effects varying by Alzheimer's-linked APOE gene type and treatment duration.
Marine-derived lysophosphatidylcholine appears to transport omega-3 DHA into the brain more efficiently than other fat forms, via a specific brain-barrier transporter protein.
A specialized brain transporter protein, MFSD2A, moves omega-3 DHA across the blood-brain barrier by binding it in a lysophosphatidylcholine form.