Evidence, in plain English

ALP Lipid Lab Library

A growing library of the omega-3 research we're following — summarized and categorized so you can find what matters to you.

Type

Population

RCT May 5, 2023

High-Dose Fish Oil in Women with Obesity: Short-Term Metabolic Boost, Longer-Lasting Anti-Inflammatory Effect

High-dose EPA+DHA supplementation improved insulin resistance and lowered inflammatory markers in women with obesity, but most benefits faded within a month after stopping, except for insulin-related and immune gene changes which lasted longer.

Cholesterol Immune System Metabolism Obesity

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Review/News Jan 12, 2026

How Omega-3s Might Support Nerve Recovery After Spinal Cord Injury

This review summarizes lab and animal research suggesting omega-3 fatty acids may support nerve health after spinal cord injury by acting through the GPR120 receptor.

Brain Cognition General Wellness Immune System

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Review/News Sep 9, 2022

Can Omega-3s Help Protect Telomeres, the Body’s Aging Clock?

A review of human studies found mixed but generally favorable evidence that higher omega-3 fatty acid levels are associated with longer telomeres, a marker linked to cellular aging.

Anti-Aging General Wellness Telomeres

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Review/News Mar 20, 2026

A Broad Look at Marine Superfoods: What Science Knows About Fish, Algae, and Seafood Compounds

This review synthesizes research on omega-3s, marine peptides, polysaccharides, and other seafood-derived compounds, outlining their proposed anti-inflammatory and antioxidant mechanisms while highlighting major gaps in human clinical evidence.

Brain Cognition Cancer General Wellness Heart Health Immune System Joints Inflammation

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RCT Feb 24, 2024

Fish Oil’s Mixed Effects on Inflammation and Liver Fat in a Mouse Model of Aging-Related Inflammation

In IL-10 deficient mice, omega-3 supplementation increased regulatory immune cells and reduced liver fat, but also raised markers of oxidative stress and lowered liver vitamin E levels.

Anti-Aging Fatty Liver Immune System Liver Health Muscle

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Review/News Mar 23, 2022

Can Special Forms of Omega-3 Fats Support Brain Health as We Age?

This review discusses how structured forms of DHA and EPA may offer better absorption and stronger anti-inflammatory/antioxidant effects than standard omega-3s, potentially relevant to brain aging.

Anti-Aging Brain Cognition General Wellness

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Review/News Mar 9, 2022

How Gut Bacteria, Butyrate, and Omega-3s May Relate to Colorectal Cancer Risk

This review found that higher omega-3 fatty acid intake was linked to greater numbers of butyrate-producing gut bacteria, a group of microbes associated with healthier colon cells and lower inflammation in colorectal cancer research.

Cancer General Wellness

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Observational Oct 24, 2021

How Omega-3s May Influence Aging: Clues from Genes, Gene Activity, and Gut Bacteria

Combining gene-marking, gene-activity, and genetic data suggests omega-3 fatty acids may influence aging-related biology partly through changes in gut bacteria and gene regulation.

Anti-Aging Cholesterol Metabolism Prenatal Pediatric

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Meta-Analysis Aug 23, 2025

Omega-3 Supplements and Recovery After Gastric Cancer Surgery

Across 32 trials, omega-3 supplementation was linked to significantly fewer infectious complications after gastric cancer surgery.

Cancer Immune System

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ALP Lipid Lab Library

High-Dose Fish Oil in Women with Obesity: Short-Term Metabolic Boost, Longer-Lasting Anti-Inflammatory Effect

How Omega-3s Might Support Nerve Recovery After Spinal Cord Injury

Can Omega-3s Help Protect Telomeres, the Body’s Aging Clock?

A Broad Look at Marine Superfoods: What Science Knows About Fish, Algae, and Seafood Compounds

Fish Oil’s Mixed Effects on Inflammation and Liver Fat in a Mouse Model of Aging-Related Inflammation

Can Special Forms of Omega-3 Fats Support Brain Health as We Age?

How Gut Bacteria, Butyrate, and Omega-3s May Relate to Colorectal Cancer Risk

How Omega-3s May Influence Aging: Clues from Genes, Gene Activity, and Gut Bacteria

Omega-3 Supplements and Recovery After Gastric Cancer Surgery

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