Evidence, in plain English

ALP Lipid Lab Library

A growing library of the omega-3 research we're following — summarized and categorized so you can find what matters to you.

Type

Population

Observational May 28, 2019

How Omega-3 DHA and Vitamin E Tocotrienol Affect Fat Droplets in Breast Cancer Cells

Combining omega-3 DHA with delta-tocotrienol reduced lipid droplet buildup and increased lipid breakdown (lipophagy) in triple-negative breast cancer cells grown in the lab.

Autophagy Cancer Gene Expression Lipophagy Metabolism

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Review/News Jul 1, 2021

How EPA Helps Kidney Cells Clear Out Excess Fat

In mice and cultured kidney cells, EPA supplementation helped restore impaired cellular 'clean-up' (autophagy) processes disrupted by excess dietary fat.

Autophagy Fatty Liver Gene Expression Lipophagy Metabolism Obesity Phospholipids

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RCT Mar 3, 2025

Omega-3s May Support Brain Function During Heat Stress by Boosting Cellular Cleanup

In heat-stressed mice, omega-3 fatty acids improved cognitive function and protected brain cells, apparently by restoring a cellular cleanup process (autophagy) through changes to the PI3K-Akt-mTOR signaling pathway.

Autophagy Brain Cognition Gene Expression

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RCT Jul 27, 2022

Krill Oil Reduced Weight Gain and Metabolic Problems in Mice Fed a High-Fat Diet

In high-fat diet-fed mice, krill oil reduced weight gain and improved markers of fatty liver, blood sugar, and kidney function.

Diabetes Fatty Liver Gene Expression Krill Oil Liver Health Metabolism Obesity

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RCT Jul 1, 2026

Plant-Based Omega-3 IV Nutrition May Support Neonatal Brain Metabolism Better Than Fish Oil Blend

In neonatal piglets, a plant-based omega-3 IV nutrition formula was linked to less brain inflammation and stronger energy and growth signaling in the brain compared to a fish-oil-based formula.

Brain Cognition Gene Expression Metabolism Plant-Based O3 Prenatal Pediatric

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Review/News Jan 1, 2022

Omega-3 Fatty Acids and Their Potential Role in Parkinson’s Disease Research

A scientific review explores how omega-3 fatty acids may influence inflammation, oxidative stress, and neuron function pathways implicated in Parkinson's disease models.

Brain Cognition Gene Expression Membranes Parkinson's Disease

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ALP Lipid Lab Library

How Omega-3 DHA and Vitamin E Tocotrienol Affect Fat Droplets in Breast Cancer Cells

How EPA Helps Kidney Cells Clear Out Excess Fat

Omega-3s May Support Brain Function During Heat Stress by Boosting Cellular Cleanup

Krill Oil Reduced Weight Gain and Metabolic Problems in Mice Fed a High-Fat Diet

Plant-Based Omega-3 IV Nutrition May Support Neonatal Brain Metabolism Better Than Fish Oil Blend

Omega-3 Fatty Acids and Their Potential Role in Parkinson’s Disease Research

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